Lookup for "450 4.7.4"
Temporary Error - This status code indicates a transient issue and may resolve itself.
Basic Status Code Details (450)
Requested mail action not taken: mailbox unavailable [E.g., mailbox busy]
Enhanced Status Code Details (4.7.4)
Security features not supported
A message contained security features such as secure authentication that could not be supported on the delivery protocol. This is useful only as a permanent error.