Lookup for "450 5.3.5"
Permanent Error - This status code indicates a permanent issue and is unlikely to resolve itself. You should contact the Email Service Provider.
Basic Status Code Details (450)
Requested mail action not taken: mailbox unavailable [E.g., mailbox busy]
Enhanced Status Code Details (5.3.5)
System incorrectly configured
The system is not configured in a manner that will permit it to accept this message.