Lookup for "450 5.7.7"
Permanent Error - This status code indicates a permanent issue and is unlikely to resolve itself. You should contact the Email Service Provider.
Basic Status Code Details (450)
Requested mail action not taken: mailbox unavailable [E.g., mailbox busy]
Enhanced Status Code Details (5.7.7)
Message integrity failure
A transport system otherwise authorized to validate a message was unable to do so because the message was corrupted or altered. This may be useful as a permanent, transient persistent, or successful delivery code.