Lookup for "501 5.1.8"
Permanent Error - This status code indicates a permanent issue and is unlikely to resolve itself. You should contact the Email Service Provider.
Basic Status Code Details (501)
Syntax error in parameters or arguments
Enhanced Status Code Details (5.1.8)
Bad sender's system address
The sender's system specified in the address does not exist or is incapable of accepting return mail. For domain names, this means the address portion to the right of the "@" is invalid for mail.