Lookup for "550 5.4.6"
Permanent Error - This status code indicates a permanent issue and is unlikely to resolve itself. You should contact the Email Service Provider.
Basic Status Code Details (550)
Requested action not taken: mailbox unavailable [E.g., mailbox not found, no access]
Enhanced Status Code Details (5.4.6)
Routing loop detected
A routing loop caused the message to be forwarded too many times, either because of incorrect routing tables or a user-forwarding loop. This is useful only as a persistent transient error.